Connective tissue diseases (CTDs) may be associated with a variety of lung abnormalities. Most patients with CTD have extra-pulmonary manifestations but in some cases, lung abnormalities are seen in isolation or as the first manifestation of disease. This chapter provides an overview of the approach to diagnosis of lung …

2017-11-29

Clinical Considerations Patients with UIP or fibrotic NSIP who have a high fibrotic score (the extent of reticulation plus HC) at TSCT and a low DLco level appear to have a high death risk [ 5 ]. In many patients the high resolution CT scan of the lungs provides enough information to confirm IPF or NSIP. In some patients there is no way to distinguish IPF from NSIP without a lung biopsy. At present, the best type of lung biopsy is a VATS (video-assisted thoracoscopic surgery).

It also falls under the umbrella of non-lymphomatous pulmonary lymphoid disorders. Nonspecific interstitial pneumonia (NSIP) is a chronic interstitial lung disease characterized by homogeneous expansion of the alveolar walls by inflammation or fibrosis or both. NSIP is the second most common chronic interstitial pneumonia, after usual interstitial pneumonia (UIP), accounting for 14% to 35% of cases. If no underlying cause is present it is known as idiopathic NSIP. Clinical features (typical) of the idiopathic form: Middle-aged, never-smoker women. Dyspnea.

In 5 to 10% of patients the chest radiograph is normal.

NSIP is the commonest pattern of CTD-related ILD, with systemic sclerosis the radiologic pathology archives: organization and fibrosis as a response to lung

Vid studier av. TKI relaterad Interventional radiology of pleural diseases. Re- spirology.

scleroderma-related interstitial lung disease (SSc-ILD) usual interstitial pneumonia (UIP) pattern: histologically indistinguishable from rheumatoid lung and idiopathic pulmonary fibrosis (IPF) an NSIP type can also occur; scleroderma-related pulmonary arterial hypertension (SSc-PAH)

NSIP is characterized by predominantly basal ground-glass opacity and/or reticular pattern, often with traction bronchiectasis. DIP and RB-ILD are smoking-related lung diseases characterized by ground-glass opacity and centrilobular nodules. COP is characterized by … Nonspecific Interstitial Pneumonia Jud W. Gurney, MD, FACR Tan-Lucien H. Mohammed, MD, FCCP Key Facts Terminology 1 of the idiopathic interstitial pneumonias, less common than idiopathic pulmonary fibrosis (IPF), but with better prognosis than IPF Imaging Findings Ground-glass opacities > reticular opacities Traction bronchiectasis out of proportion to reticular opacities May have fine Katzenstein first described NSIP in 1994.

A Honeycombing. 2017-11-29 2015-03-01 fine reticulation.
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20.4).

Pathologically and radiologically, NSIP is characterized by two patterns of lung involvement. It is thus not currently excluded that NSIP is a somewhat different response by the lung to one and the same triggering mechanism.
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Katzenstein first described NSIP in 1994. The term is used for cases of interstitial pneumonia in which diagnostic features of UIP, DIP, AIP, or COP are not present. NSIP accounts for 14–35% of biopsies performed for chronic interstitial pneumonia. Pathologically and radiologically, NSIP is characterized by two patterns of lung involvement.

NSIP. Allergisk alveolit.